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The 2nd row, labelled C for "adjust", specifies the modifications that come about if the acid dissociates. The acid focus decreases by an amount ?x, plus the concentrations of A? and H+ each improve by an sum +x. This follows from your equilibrium expression. The third row, labelled E for "equilibrium", provides together the first two rows and demo
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This reactive epoxide intermediate may well respond with amino acid residues of a CYP enzyme to form drug-CYP (drug-protein) adducts (Plan six, pathway C). The development of your drug-CYP adducts may or may not exhibit a time-dependent inactivation on the catalytic exercise of this CYP enzyme, dependant upon the covalent binding with the reactive
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